Metal chelating compounds

Details Metal chelating compounds Metal chelating compounds

C - Chemistry, Metallurgy

07

K

C07K 5/04 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01) C07C 323/41 (2006.01) C07C 323/60 (2006.01) C07D 233/91 (2006.01) C07D 309/08 (2006.01) C07D 401/06 (2006.01) C07D 405/12 (2006.01) C07F 1/00 (2006.01) C07F 13/00 (2006.01) C07F 15/00 (2006.01) C07K 5/06 (2006.01) C07K 5/083 (2006.01)

Patent

CA 2136970

2136970 9422816 PCTABScor01 Ligands for radiopharmaceutical use are capable of chelating radiometal species and of being bound to biological targeting molecules. The ligands have formula (a) and (b), where A, A' = -SZ or Y, B = O or S, Y = (c), Z = H or a thiol protecting group, m = 2 or 3, n = 2 or 3, q = 0 or 1, R = H or unsubstituted or substituted hydrocarbon and pharmaceutically acceptable salts, provided that at least one CR2 group represents CO and forms, together with an adjacent N atom, a -CONR- amide group.

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