Metal complexes and therapeutic uses thereof

Details Metal complexes and therapeutic uses thereof Metal complexes and therapeutic uses thereof

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/136 (2006.01) A61K 31/4375 (2006.01) A61K 31/496 (2006.01) A61K 31/4985 (2006.01) A61P 35/00 (2006.01) C07C 211/65 (2006.01) C07D 401/04 (2006.01) C07D 471/14 (2006.01) C07F 15/00 (2006.01)

Patent

CA 2448251

A compound of formula I or a salt thereof (I) where M is selected from the group consisting of platinum (II), palladium (II), and copper(II);L1 is an intercalator moiety; andL2 is a bidentate ligand,provided that when L2 is other than a bidentate ligand containing an aryl or phenyl group, L2 is a chiral bidentate ligand.

L'invention concerne un composé de formule (I) ou son sel, dans laquelle M est sélectionné dans le groupe constitué de platine (II), palladium (II) et cuivre (II); L¿1? désigne un fragment intercalaire et L¿2? désigne un ligand de bidentate, à condition que lorsque L¿2? est différent d'un ligand de bidentate contenant un groupe aryle ou phényle, L¿2? soit un ligand de bidentate chiral.

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