C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 15/00 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) C07C 229/16 (2006.01) C07C 229/76 (2006.01) C07C 237/10 (2006.01) C07D 257/02 (2006.01) C07D 295/26 (2006.01) C07F 5/00 (2006.01) C07F 11/00 (2006.01) C07F 13/00 (2006.01)
Patent
CA 2243316
The invention concerns new monomer perfluoroalkyl-substituted metal complexes, a process for their production, and their use in diagnostics and therapy. The compounds according to the invention to the invention are particularly suited for use as in vivo contrast agents in nuclear spin resonance tomography (MRT). They can be preferably used as blood pool agents and contrast agents for lymphography.
L'invention concerne de nouveaux complexes métalliques monomères, à substitution perfluoroalkyle, leur procédé de préparation et leur utilisation diagnostique et thérapeutique. Ces composés sont particulièrement appropriés pour être utilisés en tant qu'agents de contraste in vivo en imagerie par résonance magnétique nucléaire. Ils peuvent être employés de préférence en tant qu'agents de marquage sanguin ("blood-pool agents") et en tant qu'agents de contraste pour la lymphographie.
Ebert Wolfgang
Frenzel Thomas
Misselwitz Bernd
Niedballa Ulrich
Platzek Johannes
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Schering Aktiengesellschaft
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