Metal oxide coating of water insoluble ingredients

Details Metal oxide coating of water insoluble ingredients Metal oxide coating of water insoluble ingredients

B - Operations, Transporting

01

J

B01J 13/02 (2006.01) A01N 25/26 (2006.01) A01N 25/28 (2006.01) A01N 51/00 (2006.01) A01N 53/00 (2006.01) B01J 13/22 (2006.01)

Patent

CA 2617681

The invention relates to process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid water-insoluble particulate matter with a cationic additive in an aqueous medium to obtain a dispersion of said particulate matter having a positive zeta potential; (b) coating the solid water-insoluble particulate matter by precipitation of a metal oxide salt onto the surface of the particulate matter, forming a metal oxide layer thereon; and (c) aging said coating layer. The invention further relates to coated particulate matter obtained by the process and to compositions comprising solid, water-insoluble particulate matter, coated by a metal oxide layer, the particulate matter being a dermatological active agent or a pesticide. The invention additionally relates to methods of treating a surface condition in a subject using compositions comprising solid, water insoluble dermatologically active agent, coated by a metal oxide layer.

L'invention porte sur un procédé de revêtement d'une matière particulaire solide hydroinsoluble par un oxyde métallique consistant à: (a) mettre en contact ladite matière avec un additif cationique dans un milieu aqueux pour en obtenir une dispersion présentant un potentiel zêta positif; (b) à revêtir ladite matière par précipitation d'un oxyde métallique sur sa surface de manière à former sur elle une couche d'oxyde métallique; et (c) à laisser vieillir ledit oxyde. L'invention porte également sur la matière particulaire revêtue obtenue par ledit procédé et sur des compositions comprenant ladite matière particulaire ainsi revêtue qui peut être un agent dermatologique actif ou un pesticide. L'invention porte également sur des procédés de traitement de l'état de surfaces chez un sujet à l'aide de compositions comprenant un agent solide, hydroinsoluble et dermatologiquement actif, revêtu d'une couche d'oxyde métallique.

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