Metal-radionuclide complex comprising isonitrile ligands

Details Metal-radionuclide complex comprising isonitrile ligands Metal-radionuclide complex comprising isonitrile ligands

C - Chemistry, Metallurgy

07

F

C07F 13/00 (2006.01) A61K 51/04 (2006.01) C07C 291/10 (2006.01) C07F 1/08 (2006.01) C07F 5/00 (2006.01) C07F 7/24 (2006.01) C07F 11/00 (2006.01) C07F 15/00 (2006.01) A61K 49/02 (1990.01)

Patent

CA 2085364

2085364 9119516 PCTABS00008 The invention relates to a metal-radionuclide complex comprising isonitrile ligands, said complex having general formula (I), wherein M is a metal-radionuclide selected from radioisotopes of Tc, Ru, Fe, Cr, Mn, Cu, Pb, Ga, As and In; R1 is a straight or branched alkylene group having 2-4 carbon atoms; R2 and R3 each independently represents a methyl group or an ethyl group; R4 is a hydrogen atom or a methyl group; x is an integer from 1 to 8; and n indicates the charge of the complex and is 0 (neutral) or a positive or negative integer; with the proviso, that the total number of carbon atoms in R1 plus R2 plus R3 plus R4 is from 4 to 6. The invention also relates to a kit comprising said ligand or a metal adduct thereof.

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