C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 257/04 (2006.01)
Patent
CA 2614718
The invention relates to a method or process for the manufacture of blood pressure lowering agents, such as valsartan, novel intermediates as well as process steps in said synthesis. The method or process leads via the novel intermediate salts of the formula (IA), or a tautomer thereof, wherein [Kat]n+ is a cation and n is 1, 2, 3, 4, 5 or 6.
La présente invention concerne une méthode ou un procédé de fabrication d'agents diminuant la pression artérielle, tels que le valsartan, de nouveaux intermédiaires ainsi que des étapes de ladite synthèse. La méthode ou le procédé implique les nouveaux sels intermédiaires de formule (IA), ou un tautomère desdits sels, où [Kat]<SUP>n+</SUP> est un cation et n est égal à 1, 2, 3, 4, 5 ou 6.
Grimler Dominique
Sedelmeier Gottfried
Fetherstonhaugh & Co.
Novartis Ag
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