Metallic label in binding assay for ligand

Details Metallic label in binding assay for ligand Metallic label in binding assay for ligand

G - Physics

01

N

150/3, 167/37, 1

G01N 33/53 (2006.01) C07D 239/62 (2006.01) C07D 311/80 (2006.01) C07F 11/00 (2006.01) C07F 13/00 (2006.01) C07F 17/02 (2006.01) C07J 1/00 (2006.01) C07J 41/00 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/28 (2006.01) G01N 33/48 (2006.01) G01N 33/50 (2006.01) G01N 33/532 (2006.01)

Patent

CA 1100036

A B S T R A C T O F T H E I N V E N T I O N The present invention relates to a method and reagent means for the determination of small quantities of chemical compounds in man, animal and plants by a specific binding assay technique. The method involves the utilization of a labelling constit- uent comprising a conjugate of a labelling substance and a binding component said labelling substance being one or more metal atoms which can be easily determined. The label- ling constituents are selected from various metalo organic derivatives or metal coordination complexes. The method is very specific and sensitive and can be success- fully utilized for the determination of haptens selected from various groups such as alkaloids, barbiturates, steroids, cannabinoids, vitamins, aminoacids, tranquilizers, sugars, penicillins, etc.

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