Metallofullerene contrast agents

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 5/00 (2006.01) A61K 31/28 (2006.01) A61K 47/48 (2006.01) A61K 49/10 (2006.01) C08B 37/16 (2006.01) C08G 65/337 (2006.01)

Patent

CA 2703469

Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mM -1 S-1 to about 300 mM-1 S-1 and forms a dispersion in water with entities having an average hydrodynamic radius of less than about 20 nm.

L'invention concerne des composés métallofullerène endoèdres, qui présentent dans l'eau une relaxivité d'environ 30 mM-1S-1 à environ 300 mM-1S-1 et qui forment une dispersion dans l'eau avec des entités qui ont un rayon hydrodynamique moyen inférieur à environ 20 nm.

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