C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/37 (2006.01) A61K 51/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 14/81 (2006.01) C07K 16/40 (2006.01) C12N 9/64 (2006.01) G01N 33/52 (2006.01) G01N 33/533 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2414061
The present invention describes natural or synthetic peptide substrates of the metalloproteases, ADAM8, ADAM15 and MDC-L. The invention also describes methods using these peptides to discover pharmaceutical agents that modulate these proteases.
L'invention concerne des substrats peptidiques naturels ou synthétiques, des métalloprotéinases, ADAM8, ADAM15 et DMC-L. Elle concerne également des procédés mettant en application ces peptides afin de rechercher des agents pharmaceutiques modulant ces protéinases.
Fourie Anne
Karlsson Lars
Thurmond Robin
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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