Metalloproteinase inhibitors

Details Metalloproteinase inhibitors Metalloproteinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 233/78 (2006.01) A61K 31/4166 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61P 11/00 (2006.01) A61P 19/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 223/16 (2006.01) C07D 233/76 (2006.01) C07D 235/02 (2006.01) C07D 277/34 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 405

Patent

CA 2440632

The invention provides a metalloproteinsae inhibitor compound comprising a metal binding group having formula (I), for use in the treatment of a disease or condition mediated by one or more metalloproteinase enzymes wherein X is selected from NR1, O, S; B is C or CH, Y1 and Y2 are idenpendently selected from O, S; R1 is selected from H, alkyl, haloalkyl.

Cette invention porte sur un composé inhibiteur de métalloprotéinase, comprenant un groupe de liaison métallique représenté par la formule (I), et servant au traitement d'une maladie ou d'un état induit par une ou plusieurs enzymes de type métalloprotéinase, X étant sélectionné parmi NR1, O ou S ; B représentant C ou CH ; Y1 et Y2 étant indépendamment sélectionné parmi O ou S ; et R1 étant sélectionné parmi H, alkyle ou haloalkyle.

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