Metallotetrapyrrolic photosensitizing agents for use in...

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 5/00 (2006.01) A61K 8/49 (2006.01) A61K 31/409 (2006.01) A61K 41/00 (2006.01) A61K 49/00 (2006.01) A61P 9/00 (2006.01) A61Q 7/02 (2006.01)

Patent

CA 2448562

Metallotetrapyrrolic compounds having photherapeutics properties useful in photodetection and phototherapy of target issues, particularly porphyrins and azaporphyrins that including gallium in the central pyrrolic core. Also disclosed are methods of using metallotetrapyrrolic compounds for the treatment or detection of cardiovascular disease.

L'invention concerne des composés tétrapyrroliques métalliques présentant des propriétés photothérapeutiques. Les composés selon l'invention servent à la photodétection et à la photothérapie de tissus cibles, et se présentent notamment sous la forme de porphyrines et d'azaporphyrines contenant du gallium dans le noyau pyrrolique central. L'invention concerne également des procédés d'utilisation de composés tétrapyrroliques métalliques dans le traitement ou le diagnostic de maladies cardiovasculaires.

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