Metastasis modulating activity of highly sulfated...

A - Human Necessities – 61 – K

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A61K 31/724 (2006.01) A61K 31/715 (2006.01) A61K 31/737 (2006.01) A61K 47/48 (2006.01) C07H 11/00 (2006.01) C08B 37/16 (2006.01)

Patent

CA 2481306

The present invention provides compositions and methods for slowing tumor growth, decreasing cell proliferation, decreasing neovascularization and blocking metastatic spread using highly sulfated oligosaccharides. The compositions described herein are useful for cancer therapy and may be optionally complexed to at least one therapeutic agent.

La présente invention a trait à des compositions et des procédés permettant le ralentissement de la croissance tumorale, la réduction de la prolifération cellulaire, la réduction de la néovascularisation et le blocage de la propagation métastatique utilisant des oligosaccharides hautement sulfatés. Les compositions de l'invention sont utiles pour le traitement du cancer et peuvent éventuellement être complexées avec au moins un agent thérapeutique.

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