Metastin derivatives and their use

Details Metastin derivatives and their use Metastin derivatives and their use

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/00 (2006.01) A61P 35/04 (2006.01) C07K 5/10 (2006.01) C07K 5/107 (2006.01) C07K 7/06 (2006.01)

Patent

CA 2512553

The invention relates to metastin derivatives represented by the formula: X- AA1,-AA2-AA3-AA4.-Z (I), or a salt thereof, or a pro-drug thereof, which have cancer metastatis suppressing activity and cancer proliferation suppressing activity. The invention also relates to the use of these derivatives as drugs for preventing or treating cancers.

L'invention concerne des dérivés de métastine représentés par le formule: X-AA¿1?,-AA¿2?-AA¿3?-AA¿4?.-Z (I), ou un sel de ces derniers, ou un promédicament de ces derniers, qui possèdent une activité de suppression des métastases cancéreuses et une activité de suppression de la prolifération cancéreuse. Cette invention porte aussi sur l'utilisation de ces dérivés en tant que médicaments dans la prévention ou le traitement des cancers.

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