Metformin r-(+) lipoate as an antidiabetic agent for control...

Details Metformin r-(+) lipoate as an antidiabetic agent for control... Metformin r-(+) lipoate as an antidiabetic agent for control...

C - Chemistry, Metallurgy

07

D

C07D 339/04 (2006.01) A61K 31/385 (2006.01)

Patent

CA 2691775

Described herein is a compound of Formula (I), which is the metformin salt of the naturally occurring endogenous biological compound, (R)-(+) .alpha. lipoic acid, pharmaceutical compositions containing the compound of Formula (I), and methods of treatment of diabetes or diabetic complications with the compound of Formula (I).

L'invention concerne, d'une part un composé représenté par la formule (I), en l'occurrence le sel de metformine du composé biologique endogène naturel, a savoir l'acide (R)-(+)a-lipoïque, et d'autre part des compositions pharmaceutiques contenant ce composé, ainsi que des procédés permettant le traitement du diabète ou des complications diabétiques avec le composé de l'invention.

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