C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2421857
The method of the invention relates to a method of typing one or more nucleic acid molecules, said method comprising: simultaneously or sequentially performing two or more primer extension reactions, each primer binding at a different predetermined site in said nucleic acid molecule(s), and determining the pattern of nucleotide incorporation to obtain a test pattern for said nucleic acid molecule(s) which is optionally compared with one or more reference patterns to type the said nucleic acid molecule(s).
L'invention concerne une méthode de typage d'une ou de plusieurs molécules d'acide nucléique et consiste à exécuter de manière simultanée ou séquentielle deux réactions d'extension d'amorce ou davantage, chaque amorce se fixant au niveau d'un site prédéterminé différent dans ladite/lesdites molécule(s) d'acide nucléique, et à déterminer le type d'incorporation de nucléotide afin d'obtenir un type d'essai pour ladite/lesdites molécule(s) d'acide nucléique comparée/comparées de façon facultative à un ou à plusieurs types de référence afin de typer ladite/lesdites molécule(s) d'acide nucléique.
Ekstrom Bjorn
Pourmand Nader
Ronaghi Mostafa
Fetherstonhaugh & Co.
Pyrosequencing Ab
Qiagen Gmbh
The Board Of Trustees Of The Leland Stanford Junior University
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