Method and a system for quantitatively monitoring a chemical...

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G01N 35/00 (2006.01) B01J 19/00 (2006.01) C09B 29/00 (2006.01) C09B 41/00 (2006.01) G01N 35/08 (2006.01) G01N 21/75 (2006.01)

Patent

CA 2064037

2064037 9102254 PCTABS00003 A method and a system for quantitatively monitoring a chemical component dissolved in a liquid medium involve the creation, in a measurement chamber, of an interface zone between the liquid medium and an analytical reagent or reference solution; the measurement of the value of a measurement parameter in the interface zone, the parameter being a function of the concentration or amount of the chemical component to be monitored; and the derivation of the concentration or amount of the chemical component on the basis of the latter measured value and a baseline or reference value measured for the reagent or reference solution alone. Matrix effect(s) or ghosting error(s) are avoided. The method and the system can be used for on-line optimization and control of industrial chemical and/or biological processes, e.g. coupling reactions for the synthesis of azo compounds, monitoring of in vivo or in vitro biological systems as well as for conventional analytical purposes.

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