Method and agents for removing advanced glycosylation...

Details Method and agents for removing advanced glycosylation... Method and agents for removing advanced glycosylation...

A - Human Necessities

61

K

167/103, 167/129

A61K 39/00 (2006.01) A61K 31/70 (2006.01) G01N 33/48 (2006.01) A61K 37/02 (1990.01) A61K 49/02 (1990.01)

Patent

CA 1323565

546737 ABSTRACT The present invention relates to a method and associated agents for the inhibition and treatment of protein aging in animals by stimulating the bodies of the animals to increase their recognition and affinity for advanced glycosylation end products. Specifically, the method contemplates the administration of certain agents such as advanced glycosylation endproducts, such endproducts as are bound to the carrier, monokines that stimulate phagocytic cells to increase their activity toward advanced glycosylation endproducts, and mixtures of these materials either alone, or in conjunction with other co-stimulatory agents. Numerous diagnostic and therapeutic applications are defined, and pharmaceutical compositions are also contemplated.

546737

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