Method and apparatus for analyzing particles in a fluid

Details Method and apparatus for analyzing particles in a fluid Method and apparatus for analyzing particles in a fluid

G - Physics

01

N

G01N 15/10 (2006.01) G01N 15/14 (2006.01)

Patent

CA 2608891

A method and apparatus for analyzing particles in a fluid, such as proteinaceous particles in a pharmaceutical formulation intended for parenteral delivery, are disclosed. The method comprises arranging a fluid to form a wide and shallow stream, acquiring a sequence of magnified still images of the stream, and processing said images, so as to highlight images of particles in the flowing fluid. The apparatus includes a light source, a flow cell, a lens with increased depth of view, a detector array, and a processor for acquiring and processing the images of particles in the fluid stream.

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