Method and apparatus for analyzing the glycation of hemoglobin

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/48 (2006.01) G01N 33/66 (2006.01) G01N 33/72 (2006.01)

Patent

CA 2108011

2108011 9217107 PCTABS00016 As red blood cells age, their hemoglobin is progressively glycosylated. This invention relates to analyzing the history of blood sugar metabolism over a period of several months by taking a blood sample, separating the cells into age-ordered cohorts, determining glycohemoglobin levels in the cells of each cohort, and correlating glycohemoglobin levels with red blood cell age, while correcting for the reversibility of the Amadori rearrangement.

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