Method and apparatus for automated processing and aliquoting...

G - Physics – 01 – N

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233/1, 73/103, 7

G01N 1/28 (2006.01) B04B 5/04 (2006.01) G01N 21/07 (2006.01) G01N 33/483 (2006.01) G01N 35/00 (2006.01)

Patent

CA 1274989

Abstract METHOD AND APPARATUS FOR AUTOMATED PROCESSING AND ALIQUOTING OF WHOLE BLOOD SAMPLES FOR ANALYSIS IN A CENTRIFUGAL FAST ANALYZER A rotor and disc assembly for use in a centrifugal fast analyzer. The assembly is designed to process multiple samples of whole blood followed by aliquoting of the resultant serum into precisely measured samples for subsequent chemical analysis. The assembly requires minimal operator involvement with no mechanical pipetting. The system comprises 1) a whole blood sample disc (1), 2) a serum sample disc (17), 3) a sample preparation rotor (29), and 4) an analytical rotor (43). The blood sample disc and serum sample disc are designed with a plurality of precision bore capillary tubes (3, 19) arranged in a spoked array. Samples of blood are loaded into the blood sample disc by capillary action and centrifugally discharged into cavities (37) of the sample preparation rotor (29) where separation of serum and solids is accomplished. The serum is loaded into the capillaries (19) of the serum sample disc (17) by capillary action and subsequently centrifugally expelled into cuvettes (49) of the analytical rotor (43) for analysis by conventional methods.

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