G - Physics – 02 – B
Patent
G - Physics
02
B
117/104, 167/114
G02B 21/34 (2006.01) G01N 1/28 (2006.01) G01N 33/483 (2006.01)
Patent
CA 1095344
ABSTRACT OF THE DISCLOSURE Sample preparation apparatus for forming a thin layer of diluted blood specimen on a substrate by centrifugal force includes a sample probe having coaxial blood and diluent con- duits coupled to respective reversibly-drivable peristaltic pumps having forward operation intakes connected to a diluent supply. A one-way clutch limits the diluent pump to forward operation and the pumps are geared to produce a blood-to-diluent displacement ratio of 2:1. A substrate holder is mounted on a carriage for selective insertion into and removal from a sealed centrifuge chamber in which it is spun at a high angular rate by a drive motor. Means are provided to form a curtain of flowing liquid within the chamber surrounding the spinning substrate to collect spun-off blood particles and aerosol. The liquid forming the curtain is drained by an exhaust pump which operates after spinning has ceased so as to create partial vacuum for draining off residual aerosol prior to unsealing the centrifuge chamber.
274306
Maher Francis W. Jr.
Pirc Vladimir V.
Osler Hoskin & Harcourt Llp
Perkin-Elmer Corporation The
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