Method and apparatus for cell permeabilization

C - Chemistry – Metallurgy – 12 – N

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C12N 13/00 (2006.01) A61N 5/06 (2006.01) C12M 3/00 (2006.01)

Patent

CA 2542973

The invention relates to methods and apparatuses for introducing and releasing substances into and out of cells, and more specifically to methods and apparatuses for transiently permeabilizing a living cell so that any one or more of a variety of substances, such as ions, proteins, and nucleic acids, can be loaded into or released out of the cell.

L'invention se rapporte à des procédés et à des appareils permettant l'introduction de substances dans des cellules ainsi que la libération de substances à partir de cellules, et plus spécifiquement à des procédés et appareils permettant de perméabiliser de manière transitoire une cellule vivante de manière qu'une ou plusieurs substances quelconques sélectionnées dans une variété de substances, du type ions, protéines et acides nucléiques, puissent être chargées dans la cellule ou être libérées à partir de ladite cellule.

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