C - Chemistry – Metallurgy – 12 – M
Patent
C - Chemistry, Metallurgy
12
M
233/2, 195/45
C12M 1/00 (2006.01) B04B 1/00 (2006.01) B04B 5/04 (2006.01) C07K 16/06 (2006.01) C07K 16/30 (2006.01) C12P 19/00 (2006.01) F04B 9/02 (2006.01) F04B 43/10 (2006.01)
Patent
CA 1041445
ABSTRACT A process for augmenting production of a specific antibody from a patient including the steps of administering a specific antigen to the patient to cause production of the specific antibody, or choosing a subject containing antigen, e.g., cancer, or one already immunized or making antibodies to an endogenous or exogenous antigen, performing a thorcic duct fistula on the patient, raising the central venous pressure of the patient for example, by pericordial tamponde, and collecting lymph from the fistula, centrifuging the collected lymph to separate the lymph cells therein from the lymph fluid, and to form a thin elongated layer of the separated cells, treating the thin elongated layer of lymph cells to assure that they are sub- stantially free of the specific antibody produced, dispersing the cells in a physiologically balanced saline solution and returning the dispersed cells and solution to the patient intra- vascularly, and giving appropriate replacement therapy to main- tain normal control and health of all other systems in the body, the replacement therapy comprising fluids which can be of several kinds, but having in common that they are substantially free of the specific antibody.
196550
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