Method and apparatus for detection of biological organisms...

Details Method and apparatus for detection of biological organisms... Method and apparatus for detection of biological organisms...

G - Physics

01

N

G01N 21/65 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2628968

A method for the detection of compounds, including biological macromolecules and cells, using changes in Raman spectroscopic properties upon binding of at least one analyte binding partner. The method comprises contacting at least one analyte with at least one analyte binding partner, binding at least one analyte to at least one analyte binding partner to form a complex, and detecting the complex using the change in Raman light scattering.

La présente invention concerne un procédé de détection de composés, y compris des cellules et des macromolécules biologiques, en utilisant la modification des propriétés du spectre Raman à la suite de la liaison d'au moins un partenaire de liaison à l'analyte. Le procédé comprend la mise en contact d'au moins un analyte avec au moins un partenaire de liaison à l'analyte, la liaison du ou des analytes au partenaire ou aux partenaires de liaison à l'analyte pour former un complexe, et la détection du complexe en utilisant la modification de la diffusion de la lumière Raman.

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