G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/543 (2006.01) A61B 5/00 (2006.01) A61B 10/00 (2006.01) B01L 3/00 (2006.01) G01N 33/52 (2006.01) A61F 13/00 (2006.01)
Patent
CA 2088921
2088921 9203731 PCTABS00011 Disclosed is a method and apparatus for determining the presence of an analyte in a subject mammal's perspiration. The apparatus is a patch (52, 62, 70) that includes a water permeable support layer (20), and in certain embodiments includes a feature to detect tampering with the patch to produce false negative results. In such embodiments, this feature can comprise a reagent in a reference zone (61) that is a specific binding partner for a reference substituent in the perspiration, a soluble marker within the patch, a test region for detecting the presence of an adulterant capable of producing false negative results, an identifying marker (67) unique to each patch, or a plurality of stress razors (66). In another embodiment, the patch includes an attenuation layer (92) for attenuating the amount of light reaching the support layer for detection of photosensitive analytes. In still another embodiment, the patch (70) includes pinhole perforations (73) within a band (72) near the perimeter of the patch (70).
Miller William R.
Schoendorfer Donald W.
Sim & Mcburney
Sudor Partners
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