Method and apparatus for determining target depth,...

A - Human Necessities – 61 – B

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A61B 5/06 (2006.01) G01N 21/47 (2006.01) G01N 21/64 (2006.01)

Patent

CA 2447262

A method of investigating the location and size of a light-emitting source in a subject is disclosed. In practicing the method, one first obtains a light intensity profile by measuring, from a first perspective with a photodetector device, photons which (i) originate from the light-emitting source, (ii) travel through turbid biological tissue of the subject, and (iii) are emitted from a first surface region of interest of the subject. The light-intensity profile is matched against with a parameter-based biophotonic function, to estimate function parameters such as depth and size. The parameters so determined are refined using data other than the first measured light intensity profile, to obtain an approximate depth and size of the source in the subject. Also disclosed is an apparatus for carrying out the method.

L'invention concerne un procédé d'investigation pour déterminer la localisation et la dimension d'une source lumineuse chez un sujet. Selon ce procédé, on obtient d'abord un profil d'intensité lumineuse, à partir d'une première perspective au moyen d'un dispositif de photodétection, en mesurant des photons qui (i) proviennent de la source lumineuse, (ii) traversent le tissu biologique trouble du sujet, et (iii) sont émis par une première zone superficielle d'intérêt du sujet. Le profil d'intensité lumineuse est mis en regard d'une fonction biophotonique à base paramétrique pour estimer des paramètres de fonction tels que la profondeur et la dimension. Les paramètres ainsi déterminés sont affinés au moyen de données différentes du premier profil d'intensité lumineuse mesuré, pour obtenir une profondeur et une dimension approximatives de la source lumineuse chez le sujet. La présente invention porte également sur un appareil servant à réaliser ledit procédé.

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