B - Operations – Transporting – 01 – L
Patent
B - Operations, Transporting
01
L
B01L 3/02 (2006.01) B67D 7/08 (2010.01)
Patent
CA 2505216
A method and a micropipetting apparatus for dispensing a liquid volume into a vessel by means of a pipetting needle and without any contact between said needle and a liquid contained in said vessel. The method comprises forming a drop (17) at the delivery tip (22) of the pipetting needle (11), said drop being retained at the tip by adhesion forces, and ejecting said drop (17) from said tip (22) by focusing at the tip of the pipetting needle (11) a mechanical excitation wave applied to an excitation point at some distance from said tip (22) of the pipetting needle (11). The apparatus comprises a pipetting needle (11), an electromechanical transducer (32) mechanically connected with said pipetting needle (11), electrical signal generating means (33) for generating an excitation pulse signal (26) and for applying this signal to said electromechanical transducer (32) for mechanically exciting said pipetting needle (11) with a pulse of mechanical waves that propagate through said needle.
Méthode et dispositif de micropipettage permettant de distribuer un volume de liquide dans une cuve au moyen d'une aiguille de pipettage et sans contact entre ladite aiguille et un liquide contenu dans ladite cuve. La méthode consiste à former une goutte (17) au niveau de la pointe d'administration (22) de l'aiguille de pipettage (11), la goutte étant retenue à la pointe par des forces d'adhérence, et à éjecter la goutte (17) à partir de ladite pointe (22) en focalisant, au niveau de la pointe de l'aiguille de pipettage (11), une onde d'excitation mécanique appliquée à un point d'excitation à une certaine distance de ladite pointe (22) de l'aiguille de pipettage (11). L'appareil comprend une aiguille de pipettage (11), un transducteur électromécanique (32) relié mécaniquement à ladite aiguille de pipettage (11), des moyens de génération de signal électrique (33) pour générer un signal d'impulsion d'excitation (26) et pour appliquer ce signal vers ledit transducteur électromécanique (32) afin d'exciter mécaniquement ladite aiguille de pipettage (11) au moyen d'une impulsion d'ondes mécaniques qui se propagent à travers ladite aiguille.
Dual Juerg
Elsenhans Olivier
May Frank
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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