G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/564 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2464466
A method and apparatus for differentiation of Crohn's disease from other gastrointestinal illnesses, such as ulcerative colitis and irritable bowel syndrome, using the presence of fecal anti-Saccharomyces cerevisiae antibodies (ASCA) as a marker for Crohn's disease are provided. Figure 1 shows the presence and concentration of ASCA antibodies detected in test samples. The apparatus for differentiation of Crohn's disease from other gastrointestingal illnesses includes an enzyme-linked immunoassay or other immunoassay that utilizes antibodies specific to human immunoglobulin for the measurement of total endogenous ASCA in a human fecal sample.
L'invention porte sur un procédé et un appareil permettant de différencier la maladie de Crohn d'autres troubles gastro-intestinaux tels que la rectocolite ulcéro-hémorhagique ou le syndrome du colon irritable, utilisant la présence d'anticorps fécaux anti-Saccharomyces cerevisiae (ASCA) comme marqueurs de la maladie de Crohn. L'appareil comporte un immuno-essai lié à une enzyme ou d'autres immuno-essais utilisant des anticorps spécifiques de l'immunoglobine humaine pour mesurer l'ASCA endogène total dans un échantillon fécal humain. Le procédé et l'appareil peuvent servir au personnel de santé pour distinguer la maladie de Crohn d'autres troubles gastro-intestinaux tels que la rectocolite ulcéro-hémorhagique ou le syndrome du colon irritable.
Boone James Hunter
Lyerly David Maxwell
Wilkins Tracy Dale
Smart & Biggar
Techlab Inc.
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