Method and apparatus for efficient thin film fluid

G - Physics – 01 – N

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G01N 1/31 (2006.01) G01N 1/28 (2006.01) G02B 21/34 (2006.01)

Patent

CA 2551305

A method and apparatus for thin film fluid processing of biological samples with out rinsing between treatments is provided. An apparatus having a treatment zone for treating a biological sample with a liquid reagent, comprising first (96) and second (86) substrates having facing surfaces defining a space therebetween in which the biological sample may be treated with the liquid reagent (94), where in the first substrate comprises a relatively fluid impermeable element such as a specimen slide (96) while the second substrate comprises a relatively flexible gas permeable element, such as the membran sheet (86).

L'invention concerne un procédé et un appareil de traitement efficace faisant intervenir un liquide dans une couche mince d'échantillons biologiques sans rinçage entre les traitements. Un appareil de traitement de l'invention comprend une zone de traitement destinée à traiter un échantillon biologique avec un réactif liquide, qui comporte un premier (96) et un deuxième (86) substrat dont les surfaces opposées définissent un espace intermédiaire dans lequel un échantillon biologique peut être traité avec le réactif liquide (94) ; le premier substrat comprenant un élément relativement imperméable aux liquides de type lame (96) pour échantillon, et le deuxième substrat comprenant un élément perméable aux gaz relativement flexible, de type feuille de membrane (86).

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