Method and apparatus for enzymatic synthesis

Details Method and apparatus for enzymatic synthesis Method and apparatus for enzymatic synthesis

C - Chemistry, Metallurgy

12

M

195/143, 195/67,

C12M 1/12 (2006.01) C07K 5/072 (2006.01) C12M 1/40 (2006.01) C12P 21/00 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1309681

-14- ABSTRACT Enzyme-catalyzed synthetic reactions having otherwise unfavorable equilibria are facilitated by recovery of product by electrodialysis. Methods and apparatus are provided that can be operated continuously to produce high yields of enriched product without recourse to post-synthetic product manipulations heretofore employed that are expensive and present a risk of residual toxic by-products. The invention is applied to advantage in the preparation of alpha-L-aspartyl-L-phenylalanine lower alkyl esters. 2543Y

499619

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