Method and apparatus for forming a transdermal drug device

Details Method and apparatus for forming a transdermal drug device Method and apparatus for forming a transdermal drug device

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61L 15/44 (2006.01) A61L 15/58 (2006.01) A61M 37/00 (2006.01) B32B 31/18 (1990.01)

Patent

CA 2126366

ABSTRACT Disclosed is a method and apparatus for forming a transdermal drug delivery device from a multilayer web comprised of a backing layer, a drug- containing pressure sensitive adhesive layer, and a release layer or liner in which cutting is progressively achieved along a line coplanar with the axes of a cutting roller and anvil roller counter-rotating in proximity to each other. In one embodiment, cutting is achieved completely through the web about the periphery of the transdermal drug delivery device, while simultaneously achieving a scoring only of the release liner without penetration of the pressure sensitive adhesive layer or backing layer. In an alternate embodiment there are two arrangements of rollers. A first arrangement has a cutting edge for scoring the web. After scoring, the web is passed to a second arrangement for cutting through the web to result in the transdermal drug delivery device.

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