Method and apparatus for fourier transform ion cyclotron...

H - Electricity – 01 – J

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H01J 49/26 (2006.01) H01J 49/14 (2006.01) H01J 49/40 (2006.01) H01J 49/42 (2006.01)

Patent

CA 2621126

A novel method and apparatus for Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FTICR-MS). The FTICR-MS apparatus has a pre-ICR mass separation and filtering device capable of receiving ionized molecules with a plurality of mass to charge (M/Z) sub-ranges. The pre-ICR mass separation and filtering device divides the ionized molecules into a plurality of smaller packets, each of the smaller packets is within one of the M/Z sub-ranges. A magnet in the FTICR-MS apparatus provides a controlled magnetic field. A plurality of ion cyclotron resonance (ICR) cells are arranged in series in the controlled magnetic field and operate independently. An ion trapping device connects the pre-ICR mass separation and filtering device, and stores one of the plurality of smaller packets, prior to sending it to one of the plurality of ICR cells.

La présente invention concerne un procédé et un appareil pour spectrométrie de masse ICR-FTMS. L'appareil comporte un étage pré-ICR (Ion Cyclotron Resonance) de séparation et filtrage de masse capable de recevoir des molécules ionisées comportant une pluralité de sous-intervalles masse à charge (M/Z). L'étage pré-ICR partage les molécules ionisées en une pluralité de paquets plus petits tenant chacun dans l'un des sous-intervalles M/Z. Dans l'appareil ICR-FTMS, un aimant produit un champ magnétique contrôlé. Des cellules de résonance cyclotron des ions (ICR) montées en série dans le champ magnétique contrôlé fonctionnent indépendamment. Un piège à ions relié au dispositif pré-ICR de séparation et de filtrage de masse conserve l'un des paquets de la pluralité de paquets plus petit avant de l'envoyer à la pluralité de cellules ICR.

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