Method and apparatus for nitric oxide generation

A - Human Necessities – 61 – K

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A61K 33/00 (2006.01) A61K 9/12 (2006.01) A61K 9/20 (2006.01) A61K 9/72 (2006.01) A61K 33/24 (2006.01) A61K 33/30 (2006.01) A61K 33/34 (2006.01) A61K 47/30 (2006.01) A61M 15/00 (2006.01) A61M 16/00 (2006.01) A61M 16/10 (2006.01) A61M 16/12 (2006.01) A61N 1/04 (2006.01) A61K 9/00 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2459891

Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.

Selon l'invention, l'inhalation de bas niveaux d'oxyde nitrique peut rapidement et en toute sécurité diminuer l'hypertension pulmonaire chez les mammifères. L'administration précise d'oxyde nitrique à des niveaux thérapeutiques compris entre 20 et 100 ppm et le fait d'inhiber la réaction de l'oxyde nitrique avec l'oxygène pour former des impuretés toxiques telles que du dioxyde d'azote peut constituer une inhalothérapie efficace contre l'hypertension pulmonaire.

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