Method and apparatus for optimizing cardiac...

A - Human Necessities – 61 – N

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A61N 1/365 (2006.01) A61B 5/00 (2006.01) A61B 5/02 (2006.01)

Patent

CA 2519256

A method and apparatus for optimizing cardiac resynchronization therapy are provided. An iterative optimization procedure is performed to test the systolic hemodynamic effects of varying A-V-V timing schemes. The hemodynamic effect is assessed based on a surrogate of stroke volume. The stroke volume surrogate is derived from a sensor signal proportional to the blood pressure in the aorta or a major artery. The A-V-V timing scheme corresponding to the greatest stroke volume, as indicated by the stroke volume surrogate, is identified and automatically programmed to maintain optimal A-V-V settings acutely and chronically.

L'invention concerne un méthode et un appareil destinés à optimiser une thérapie de resynchronisation cardiaque. Une procédure d'optimisation itérative est exécutée pour tester les effets hémodynamiques systoliques de schémas de synchronisation A-V-V variable. L'effet hémodynamique est évalué sur la base d'un substitut de volume d'éjection systolique. Le substitut de volume d'éjection systolique est dérivé d'un signal de détecteur proportionnel à la pression artérielle dans l'aorte ou une artère principale. Le schéma de synchronisation A-V-V correspondant au volume d'éjection systolique le plus élevé, tel qu'indiqué par le substitut de volume d'éjection systolique, est identifié et programmé automatiquement pour maintenir des valeurs A-V-V optimales de façon perspicace et chronique.

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