Method and apparatus for parallel dispensing of defined...

Details Method and apparatus for parallel dispensing of defined... Method and apparatus for parallel dispensing of defined...

G - Physics

01

N

G01N 35/10 (2006.01) B01L 3/02 (2006.01) B01L 7/00 (2006.01) B01L 7/02 (2006.01) G01N 35/00 (2006.01) G01N 35/02 (2006.01)

Patent

CA 2464467

A sample preparation system(100) provides an automated process that dispenses appropriate amounts of solid material into wells of a microtiter plate for mixing into a suspension. The system utilizes an array of hollow tubes(1802) that are lowered into a particle reservoir(204) such that particle material is forced up into the tubes. During loading, solid plungers(1808) in the tubes are positioned a known distance from the open end of the tubes. When the particle material is to be dispensed, the plungers are lowered to push the particle material out of the tubes and into receiving wells(204) of the microtiter plate. The plunger stroke and internal diameter of the tubes defines the dispensed volume of particle material.

L'invention concerne un système de préparation d'échantillons qui fait intervenir un procédé automatique au moyen duquel des quantités appropriées de matières solides sont distribuées dans les puits d'une plaque de microtitrage pour les mélanger et former une suspension. Ce système comprend un jeu de tubes creux qui sont plongés dans un réservoir de particules pour forcer la matière particulaire à pénétrer dans les tubes dans une direction ascendante. Au cours de la charge, des pistons solides logés dans les tubes sont placés à une distance connue de l'extrémité ouverte des tubes. Au moment de la distribution de la matière particulaire, les pistons sont abaissés pour expulser la matière particulaire des tubes vers les puits de réception de la plaque de microtitrage. La course du piston ainsi que le diamètre interne des tubes permettent de déterminer le volume de matière particulaire distribué.

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