Method and apparatus for preparing an acellular red blood...

A - Human Necessities – 61 – K

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A61K 38/42 (2006.01) C07K 14/805 (2006.01) C08H 1/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2250274

A process is disclosed for the preparation of an essentially tetramer-free, substantially stroma-free, polymerized, pyridoxylated hemoglobin. Also disclosed is an essentially tetramer-free, substantially stroma-free, polymerized, pyridoxylated hemoglobin product capable of being infused into human patients in an amount of up to about 5 liters.

Procédé de préparation d'une hémoglobine pyridoxylée, polymérisée, sensiblement dépourvue de stroma et essentiellement dépourvue de tétramères. Un produit à base d'hémoglobine pyridoxylée, polymérisée, sensiblement dépourvue de stroma et essentiellement dépourvue de tétramères est également décrit, ce produit pouvant être injecté à des patients humains selon des quantités allant jusqu'à environ 5 litres.

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