A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 38/27 (2006.01) A61K 38/28 (2006.01) B01D 1/18 (2006.01) B01F 3/08 (2006.01) B01F 5/06 (2006.01) B01J 2/04 (2006.01) B01J 2/10 (2006.01)
Patent
CA 2478629
Method and apparatus for producing dry particles. Two liquid components are combined in a static mixer (230, 630), atomized into droplets, and the droplets dried to form dry particles. Use of the static mixer (230, 630) enables incompatible liquid components to be rapidly and homogeneously combined. The present invention optimizes process conditions for increasing and controlling particle porosity. The present invention also allows for optimization of particle size in real-time during particle production.
La présente invention concerne un procédé et un appareil de production de particules sèches. Deux composants liquides se combinent dans un mélangeur statique (230, 630) donnant par atomisation des gouttelettes qui sont séchées pour former les particules sèches. Le mélangeur statique (230, 630) permet une combinaison rapide et homogène de composants liquides incompatibles. La présente invention, qui optimise les conditions de traitement pour augmenter et contrôler la porosité des particules, permet également l'optimisation du calibre des particules, en temps réel pendant la production des particules.
Batycky Richard P.
Blizzard Charles D.
Chung Marie Elizabeth
Jackson Blair C.
Johnston Lloyd P.
Advanced Inhalation Research Inc.
Alkermes Inc.
Smart & Biggar
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