Method and apparatus for screening chemical compounds

Details Method and apparatus for screening chemical compounds Method and apparatus for screening chemical compounds

G - Physics

06

T

G06T 7/00 (2006.01) G01N 21/64 (2006.01)

Patent

CA 2426798

Methods and apparatus for screening large numbers of chemical compounds and performing a wide variety of fluorescent assays, including live cell assays. The methods utilize a laser linescan confocal microscope with high speed, high resolution and multi-wavelength capabilities and real time data-processing. Imaging may be done at video-rates and with use of ultraviolet illumination.

La présente invention concerne des procédés et des dispositifs permettant de cribler des grands nombres de composés chimiques et de réaliser une large gamme d'essais biologiques fluorescents, y compris des essais biologiques sur des cellules vivantes. Les procédés décrits dans cette invention consistent à utiliser un microscope confocal à balayage linéaire par laser grande vitesse, haute résolution et à longueurs d'ondes multiples, et à exécuter un traitement des données en temps réel. L'imagerie peut être réalisée à des débits vidéos et à l'aide d'un éclairement ultraviolet.

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