C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/60 (2006.01) G01N 33/68 (2006.01) G01T 1/164 (2006.01)
Patent
CA 2434093
The present invention relates to a method and apparatus for simultaneous quantification of the amounts of one or more radioactive nuclides within arbitrary regions on a surface where these nuclides have been deposited, adsorbed or fixed. These radioactive nuclides serve as markers on compounds that typically have been incorporated into tissue sections or into larger biological molecules that by various mechanisms have been bound to chemical substances on this surface. The method is especially well suited for DNA microarray deductions through the use of nucleotides labelled with different beta-emitting radionuclides.
L'invention concerne un procédé et un appareil de quantification simultanée de la quantités d'un ou plusieurs radionucléides dans des zones arbitraires sur une surface où ces radionucléides ont été déposés, absorbés ou fixés. Ces radionucléides servent de marqueurs sur des composés qui ont été incorporés dans des sections de tissus ou dans des molécules biologiques plus grandes qui au moyen de divers mécanismes ont été liées à des substances chimiques sur cette surface. Le procédé de l'invention convient particulièrement aux déductions de microréseau d'ADN au moyen des nucléotides étiquetés avec différents radionucléides à émission bêta.
Breistol Knut
Hovig Eivind
Kvinnsland Yngve
Nygard Einar
Skretting Arne
Biomolex As
Goudreau Gage Dubuc
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