Method and apparatus for spectrometric analysis of turbid,...

Details Method and apparatus for spectrometric analysis of turbid,... Method and apparatus for spectrometric analysis of turbid,...

G - Physics

01

N

G01N 21/35 (2006.01) G01J 3/44 (2006.01) G01N 21/25 (2006.01) G01N 21/47 (2006.01) G01N 21/53 (2006.01) G01N 33/15 (2006.01) G01N 21/33 (2006.01) G01N 21/39 (2006.01) G01N 21/51 (2006.01)

Patent

CA 2383834

The present invention relates to a method and an apparatus for use in performing a quantitative analysis of a turbid pharmaceutical sample, e.g. a tablet, a capsule or a similar sample forming a pharmaceutical dose. A pharmaceutical, turbid sample (24) is irradiated with an excitation beam (20) of radiation, e.g. near infrared radiation. The intensity of emitted radiation (30) from the sample (24) is detected as a function of both the wavelength of the emitted radiation and the photon propagation time through said sample (24). Optionally, the intensity of the emitted radiation (30) from the sample (24) is also detected in a spatially resolved manner.

La présente invention concerne un procédé et un appareil destinés à être utilisés pour effectuer une analyse quantitative d'un échantillon pharmaceutique trouble, par exemple, un comprimé, une capsule ou autre échantillon similaire constituant une dose pharmaceutique. A cet effet, on soumet l'échantillon pharmaceutique (24) trouble à un faisceau (20) de rayonnement d'excitation, notamment un rayonnement proche de l'infrarouge. L'intensité du rayonnement (30) émis par l'échantillon (24) est détectée sous la forme d'une fonction de la longueur d'onde du rayonnement émis et du temps de propagation des photons dans ledit échantillon (24). Eventuellement, l'intensité du rayonnement (30) émis par l'échantillon (24) est également détectée de manière spatialement résolue.

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