Method and apparatus for the measurement of components of...

G - Physics – 01 – N

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G01N 33/497 (2006.01) A61B 5/097 (2006.01) G01N 33/50 (2006.01) G01N 33/84 (2006.01) A61B 5/083 (2006.01)

Patent

CA 2252024

Methods and related equipment for measuring components of exhaled breath of a subject are provided which involve causing the subject to exhale into an appropriate apparatus for receiving exhaled breath; increasing the pressure in the mouth of the subject to a level sufficient to close the vellum and isolate the nasopharynx during exhalation; a means of monitoring nasal CO2 to confine vellum closure; and measuring the level of one or more components of the collected exhaled breath. Endogenous nitric oxide is a preferred component of exhaled breath for monitoring and analysis.

La présente invention, qui concerne des procédés de mesure des composants de l'haleine d'un sujet, concerne également un matériel approprié. Le procédé consiste à faire exhaler le sujet dans un appareil conçu pour recueillir l'haleine tout en faisant monter la pression dans la bouche du sujet jusqu'à un niveau provoquant la fermeture du voile du palais et l'isolation du rhino-pharynx. Un organe surveille le niveau de CO2 de façon à confirmer la fermeture du voile du palais. Ce dispositif est conçu pour mesurer la teneur de l'haleine exhalée recueillie en l'un ou de plusieurs de ses composants. La surveillance et l'analyse porte de façon préférentielle sur un composant d'haleine exhalée: le monoxyde d'azote endogène.

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