Method and apparatus for the preparation of blood samples...

G - Physics – 01 – N

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150/11

G01N 1/28 (2006.01)

Patent

CA 1129320

ABSTRACT A method for preparing blood samples contain- ing red blood cells for automated analysis wherein the blood sample on a slide (20) is spun to create a mono- layer of randomly distributed red blood cells (40, 42, 46). To inhibit cell morphology distortions from oc- curring during drying. The morphologies of the cells contained in the monolayer are preserved by a fixing agent after monolayer preparation but prior to drying when such distortions would otherwise develop. The method and apparatus are particularly useful for fixing red blood cells to prevent loss of or deformation of a central pallor which would be detrimental to a sub- sequent automated analysis. A vaporous fixing agent may be conveyed through a conduit (26) into a spinning chamber (14) enclosed by a cover (24) of a slide spin- ning apparatus to provide a fixing atmosphere therein to begin fixing the wet cell before they can dry.

330583

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