Method and apparatus for treating tissue with first and...

Details Method and apparatus for treating tissue with first and... Method and apparatus for treating tissue with first and...

A - Human Necessities

61

M

327/1, 326/16, 1

A61M 37/00 (2006.01) A61F 7/12 (2006.01) A61N 5/00 (2006.01) A61N 5/10 (2006.01)

Patent

CA 1336317

Method and apparatus is disclosed for treating tissue interstitially with multiple modalities of treatment. The apparatus comprises a semi-rigid elongated member that is implanted interstitially in the malignant tumor. A hollow passageway is longitudinally positioned in the member for positioning one or more modalities inserted or positioned therein. The elongated member is coated with another modality such as a carrier substance that is responsive at a temperature above normal tissue temperature for releasing a carried substance such as a therapeutic anti-cancer drug. Within the elongated member, an electrical heater element for one modality produces heat when energized for heating the probe, the carrier substance, the anti-cancer drug, and the surrounding tissue. A second modality such as a source of radiation is inserted in the passageway after the probe is interstitially implanted. A trocar stylet is initially inserted in the passageway to implant the probe. When the probe is implanted, the trocar stylet is removed, and the heater element and/or source of radiation is inserted into the passageway. The several modalities combine in a synergistic manner to provide an overall treatment that has an effectiveness level greater than the sum of the individual modalities.

610058

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