Method and apparatus for two-dimensional measurement of...

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G01N 21/59 (2006.01) B01D 9/00 (2006.01) G01N 25/14 (2006.01) G01N 21/33 (2006.01)

Patent

CA 2057558

METHOD AND APPARATUS FOR TWO-DIMENSIONAL MEASUREMENT OF CONCENTRATION OF BIOLOGICAL MACROMOLECULE CONCENTRATION ABSTRACT OF THE DISCLOSURE A method of making a two-dimensional measurement of the concentration of a biological macromolecule aqueous solution and an apparatus for carrying out this method are disclosed. By charging the biological macromolecule aqueous solution and an aqueous crystallizing agent solution into a crystallizing cell, irradiating the crystallizing cell with an ultraviolet light from an ultraviolet light source, two-dimensionally scanning the ultraviolet light transmitted through the crystallizing cell by a linear sensor to detect the quantity of the transmitted light, and carrying out a conversion of the detected quantity of the transmitted light to the protein concentration, the process of a crystallization of the biological macromolecule from biological macromolecule aqueous solution can be easily and accurately two- dimensionally measured.

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