Method and composition for controlling proliferation of cells

Details Method and composition for controlling proliferation of cells Method and composition for controlling proliferation of cells

C - Chemistry, Metallurgy

12

N

C12N 5/02 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) C07K 14/47 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2091759

2091759 9205272 PCTABS00011 A method and composition for reversibly increasing the proliferation of cells in vitro. Cell populations are treated in vitro) with antisense oligonucleotides to a tumor suppressor gene, such as the retinoblastoma (Rb) gene. Such treatment inhibits expression of the tumor suppressor gene product and results in a reversible increse in the proliferation of the cell population.

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