Method and composition for potentiating an opiate analgesic

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/06 (2006.01) A61K 31/4025 (2006.01) A61K 31/422 (2006.01) A61K 31/485 (2006.01) A61K 31/506 (2006.01) A61K 38/12 (2006.01) A61K 38/17 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2464768

Composition and methods of treating pain and reducing or reversing tolerance to opiate analgesics are disclosed. The composition and method utilize an opiate analgesic and an endothelin antagonist as active agents to treat pain in mammals, including humans.

L'invention concerne une composition et des méthodes permettant de traiter et de réduire ou d'inverser la tolérance aux analgésiques opioïdes. Lesdites composition et méthode utilisent un analgésique opioïde et un antagoniste des récepteurs de l'endothéline comme agents actifs pour traiter des mammifères, notamment des humains.

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