G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 1/30 (2006.01) A01N 1/00 (2006.01) A61K 39/00 (2006.01) A61K 39/39 (2006.01) C12Q 1/00 (2006.01) G01N 33/531 (2006.01) G01N 33/577 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2123227
A method and composition for fixing and stabilizing tissues, cells, and cell components such that the antigenic sites are preserved for a useful period of time is provided. The fixative employs a formaldehyde donor that is non-toxic, non-flammable, and that stabilizes the cell with minimal damage to and alteration of the cell morphology. The cell antigenic sites are left intact so that studies with monoclonal antibodies may be conducted. Vaccines and related immunotherapeutic methods utilizing antigens stabilized by the fixative of the present invention are also provided. The invention also discloses a method for developing a posi-tive control for test reagents and for test instrumentation.
Macrae & Co.
Streck Laboratories Inc.
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