Method and composition for preserving viruses

Details Method and composition for preserving viruses Method and composition for preserving viruses

C - Chemistry, Metallurgy

12

N

C12N 7/00 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2351890

The present invention provides a method and a composition for preserving a virus. The virus is placed in a liquid carrier with a stabilizing agent selected from the group consisting of polysorbate 80, L-arginine, polyvinylpyrrolidone, trehalose, and combinations thereof. The liquid composition can be maintained at a temperature above 0 ~C for a significant period of time while maintaining a satisfactory degree of viral activity.

L'invention concerne une méthode et une composition permettant de conserver un virus. Le virus est placé dans un excipient liquide avec un agent de stabilisation sélectionné dans le groupe constitué par le polysorbate 80, la L-arginine, la polyvinylpyrrolidone, le tréhalose, et des combinaisons de ces derniers. La composition liquide peut être maintenue à une température supérieure à 0 ·C pendant longtemps et conserver un taux satisfaisant d'activité virale.

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