A - Human Necessities – 61 – B
Patent
A - Human Necessities
61
B
A61B 17/02 (2006.01) A61F 2/02 (2006.01) A61K 31/755 (2006.01) A61K 31/77 (2006.01) A61L 27/00 (2006.01) A61L 31/04 (2006.01)
Patent
CA 2361585
An improved method for preventing adhesions during surgery. Tissue surfaces and surgical articles involved in the surgery are coated with a solution of a hydrophilic, polymeric material prior to manipulation of the tissue during surgery. The polymeric material is: (1) a substantially water-soluble polymer having at least one CnF2n+1 substituent wherein n >= 4, having a molecular weight of less than about 60,000; (2) a pharmaceutically acceptable salt or complex thereof; or (3) mixtures thereof. The concentration of the aqueous solution of the polymeric material is in the range of from about 0.1 % to about 5.0 % by weight, the molecular weight and concentration having values such that the aqueous solution is capable of providing wet coatings on the tissue.
Méthode améliorée de prévention d'adhésions pendant une chirurgie. Des surfaces tissulaires et des articles chirurgicaux appliqués dans la chirurgie sont revêtus d'une solution d'une matière hydrophile polymère avant la manipulation des tissus au cours de la chirurgie. La matière polymère est (1) un polymère sensiblement hydrosoluble présentant au moins un substituant C¿n?F¿2n+1? dans lequel n >= 4, ayant une masse moléculaire inférieure à environ 60 000; (2) un sel acceptable sur le plan pharmaceutique ou son complexe; ou (3) des mélanges de ceux-ci. La concentration de la solution aqueuse de la matière polymère se situe dans la gamme allant d'environ 0,1 % à environ 5,0 % en poids, la masse moléculaire et la concentration ayant des valeurs telles que la solution aqueuse soit capable de former des revêtements humides sur les tissus.
Goldberg Eugene P.
Kirk James F.
Peck Lynn S.
Gowling Lafleur Henderson Llp
University Of Florida
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