Method and composition for regulating serum calcium levels...

Details Method and composition for regulating serum calcium levels... Method and composition for regulating serum calcium levels...

A - Human Necessities

61

K

167/103.46

A61K 9/10 (2006.01) A61K 9/127 (2006.01) A61K 38/23 (2006.01) A61K 38/29 (2006.01)

Patent

CA 1277595

A METHOD AND COMPOSITION FOR REGULATING SERUM CALCIUM LEVELS OF MAMMALS Abstract of the Disclosure Method for regulating serum calcium levels in mammals by orally administering a composition which includes a polypeptide hormone such as parathyroid hormone (PTH) or calcitonin. The polypeptide hormone is protected from destruction in the digestive tract by encapsulation in liposomes. The liposome preferably includes a cationic amphiphilic agent so that the surface of the liposome has a net positive charge. Agents for enhancing the action of the liposome encapsulated hormones are also disclosed.

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